Long-Term Effects of Alcohol Abuse The negative\u00a0effects of\u00a0alcohol abuse go far beyond nasty hangovers and beer guts. Over time, alcohol can wreak havoc on the body, contributing to more than 200 diseases and injury-related health conditions. Heavy alcohol use also negatively affects your mind. It is associated with increased depression and other co-occurring mental disorders, job and relationship problems, and violent behavior. Excessive drinking \u2014 which includes binge and heavy drinking \u2014 is far more common than alcoholism. Some people with alcohol use disorder will require inpatient rehab\u00a0and medical detox to\u00a0heal from the ravages\u00a0of alcohol use. The following infographic takes you on a trip through time, highlighting how alcohol can affect your work, relationships and health throughout life.