See which 10 television characters would likely be diagnosed with a serious substance use disorder if they really walked among us. Tyrion Lannister, \u201cGame of Thrones\u201d Tyrion swills and guzzles his way through the ups and downs of The Seven Kingdoms. Granted, he hasn\u2019t had the easiest time of it. His mother died giving birth to him, his sister and father resent him for it, and with nicknames like \u201cthe imp\u201d and \u201cthe halfman,\u201d which unapologetically mock his dwarfism, we can see why he may turn to the bottle. Tyrion is a self-medicator. He hasn\u2019t learned how to cope with his hardships so he numbs with alcohol. \u201cIt\u2019s not easy being drunk all the time. If it were easy, everyone would do it,\u201d he says. Actually, many of his comrades seem up to the challenge. Jesse Pinkman, \u201cBreaking Bad\u201d Oh, Jesse. We\u2019re all rooting for you, but your squirm-worthy string of bad decisions makes it so difficult sometimes. Jesse has bouts of sobriety, but when times get tough he likes to reach for the meth pipe. Not to mention his dangerous dance with heroin, compliments of the troubled Jane Margolis. We won\u2019t even talk about her heartbreaking fate. Jesse (and Jane) should not pass go, should not collect $200 and head straight to drug rehab. Jimmy McNulty, \u201cThe Wire\u201d His drinking habits are so infamous they\u2019ve even made their way into pop culture. Per the Urban Dictionary: \u201cMcNulty \u2014 A pint of Jameson whiskey. In reference to Det. Jimmy McNulty from The Wire, who is known to carry and drink a pint of Jameson wherever he goes.\u201d Jimmy is a functioning alcoholic. He somehow manages to hold down a job, but that\u2019s about the only thing he hasn\u2019t messed up. A functioning alcoholic is still an alcoholic, and this one needs alcohol rehab to get clean. Though the end of the series finds Jimmy sober again, without addiction treatment, he\u2019s bound to fall into the same patterns. Jackie Peyton, \u201cNurse Jackie\u201d She\u2019s so loveable and charming. That\u2019s why it makes it particularly heartbreaking to watch her struggle with drug abuse and failed attempts to get sober. Nurse Jackie is the poster child for prescription drug addiction. Percocet, Xanax, Vicodin \u2014 pretty much whatever\u2019s handy at the time is her drug of choice. She lies, cheats, steals and breaks just about every rule in the Nursing Code of Ethics. Jackie is a chronic relapser and needs a serious, long-term stint in a comprehensive drug rehab to reverse her fate. Frank Gallagher, \u201cShameless\u201d Blackouts, arrests, tumultuous relationships, chronic unemployment, health problems \u2014 Frank has all the traits of a classic alcoholic. He continues his downward, booze-infused spiral despite the negative consequences \u2014 one of the No. 1 signs of addiction. Fans have even created a Shameless Drinking Game where people drink every time \u201cFrank does something to completely and utterly screw over the family.\u201d And P.S. readers, if you\u2019re playing that drinking game, you might want to take a look at your alcohol consumption, too. Norm Peterson, \u201cCheers\u201d The entire bar greets him by name every time he walks through the door, and he has his own designated barstool. Enough said. Lucille Bluth, \u201cArrested Development\u201d The matriarch of the colorful Bluth crew, she has a martini in her hand at all times. Did her eccentric family drive her to drink or did her drinking help propel their dysfunction? Our hunch is the latter. At her first intervention, the family got drunk and it turned into a party. Their second attempt to get Lucille into alcohol rehab was more successful, but ended in a drinking game \u2014 that she won. It\u2019s time to put down that martini and get to alcohol detox and a successful alcohol abuse program. Dr. Gregory House, \u201cHouse\u201d He\u2019s a doctor. He should know better, right? Not always. Unfortunately the incorrigible Dr. House\u2019s painkiller addiction is not the exception to the rule. Researchers estimate that 10% to 15% of all healthcare professionals misuse drugs or alcohol during their careers. Through six seasons we watch House abuse Vicodin, LSD, oxycodone and methadone. His stretch in Mayfield Psychiatric Hospital curbs his addiction for a while, but he\u2019s back on drugs the next time life throws him a curveball. House needs to thoroughly address the underlying issues that propel his drug use and learn healthier coping skills. Don Draper, \u201cMad Men\u201d What kind of substance abuse list would this be without the dreamy but damaged ad exec, Mr. Draper? He flawlessly fit into the cocktail culture of the 1960s corporate powerhouses. But social drinking is sometimes a slippery slope into full-blown substance abuse, and my friend, he has slid. Liquid lunches quickly progressed into late-night bar boozing, drug experimentation and alcohol-powered situations like vomiting at a funeral, spending the night in the slammer, delirium tremens and even punching a minister while on the sauce. Don has lost his job and his loved ones. His life is unmanageable. He needs alcohol rehab and some intensive therapy to heal from those childhood trauma wounds that are likely fueling his destructive behaviors. Penny Hofstadter, \u201cThe Big Bang Theory\u201d She\u2019s rarely seen without wine in hand. Blacking out, inebriated promiscuity, passing out while her friends play Twister around her, not to mention that one time she woke up in bed with Raj \u2013 these are just some of Penny\u2019s drunken antics. Behind that effervescent exterior is a woman struggling with substance use issues. She self-medicates with alcohol when she\u2019s sad and celebrates with it when she\u2019s happy. Her friends, who aren\u2019t exactly the poster children for sobriety, have even expressed concerns about her drinking. Though she seems to have tamed her ways in recent seasons, we can\u2019t help but wonder if the binge drinking will start up again with just the right trigger. Can You Relate? Watching the trials and tribulations of our TV friends on the little screen is one thing. Recognizing a lot of ourselves or a loved one in those characters\u2019 alcohol or drug use is quite another thing. If dramatic depictions of personalities like Penny, Don and Jimmy hit a little too close to home, it may be time to see if fiction is mirroring reality.